Buy IGF-1 LR3 1mg
Long Arg3 IGF-1 — extended half-life IGF analog with 100× longer activity than native IGF-1. The anabolic peptide for muscle research.
Product Specifications
- Chemical
- Long Arg3 Insulin-like Growth Factor-1
- CAS Number
- 946870-92-4
- Purity
- ≥98% HPLC verified
- Form
- Lyophilized powder
- Storage
- −20°C long-term / 2–8°C reconstituted
- SKU
- PG-1004
Why Buy IGF-1 LR3 1mg from Peptide Scientists
IGF-1 LR3 is the long-lived analog of insulin-like growth factor-1 — engineered for ~20-30 hour activity vs the 12-15 minute half-life of native IGF-1. Buying it online provides access to the most studied anabolic peptide in muscle research.
Our 1mg vial is the standard research format. ≥98% HPLC and SDS-PAGE verified purity, sourced from Phiogen with full documentation.
$79.99 for the 1mg vial — covers extended research protocols at the standard 20-50mcg/day dose.
About IGF-1 LR3 1mg
IGF-1 LR3 (Long Arg3 Insulin-like Growth Factor-1, CAS: 946870-92-4) is a recombinant analog of native IGF-1 with two modifications: an N-terminal 13-amino acid extension and an Arg substitution at position 3 (replacing glutamic acid).
These modifications reduce IGFBP (IGF binding protein) affinity by >1000-fold. Native IGF-1 is >99% bound to IGFBPs in circulation, limiting bioavailability. IGF-1 LR3 remains in free, active form with a half-life of approximately 20-30 hours — a ~100× increase.
Mechanism: activates the IGF-1 receptor (IGF-1R, a receptor tyrosine kinase), driving the PI3K/Akt/mTOR pathway (protein synthesis, cell growth, satellite cell activation) and Ras/MAPK pathway (proliferation, differentiation).
Key Features
- 100× longer half-life than native IGF-1 (20-30 hours vs 12-15 minutes)
- IGFBP-independent — remains in free active form
- PI3K/Akt/mTOR pathway activation for protein synthesis
- Standard anabolic research peptide
- ≥98% HPLC verified, free US shipping over $200
Frequently Asked Questions
What's the difference between IGF-1 LR3 and regular IGF-1?
How is IGF-1 LR3 administered?
Does IGF-1 LR3 stack with GH-releasing peptides?
Why is IGF-1 LR3 stored differently from other peptides?
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Laboratory Use Only. This product is sold for in-vitro laboratory use. Not for human consumption, injection, or therapeutic application. Consult applicable regulations in your jurisdiction.
IGF-1 LR3 1mg
$79.99